Advanced Mechanistic PK/PD Modeling with PK-Sim® & MoBi®

Date: Thursday, April 7, 2011

Registration Fees: $500 non-students; $50 students

Maximum class size: 30

Sponsor: Bayer Technology Services GmbH

Instructors/Teaching Assistants: Jörg Lippert, Martin Hobe, Stefan Willmann

Schedule: Note, specific times are subject to change based on alignment with concurrent ACoP workshops

9:00 am     Introduction into mechanistic multiscale modeling and presentation of workshop case study
9:45 am     Modeling intracellular signaling processes and molecular mechanism of action
11:00 am   Coffee break
11:15 am   Modeling tumor growth
                 Integration of intracellular and cellular models
12:30 pm  Lunch
1:30 pm    Establishment of a prodrug-active metabolite PBPK model
2:30 pm    Integration of models and establishment of multi-scale cancer patient model
3:30 pm    Coffee break
3:45 pm    Population simulation of two pharmacogenomics case studies and analysis of simulated endpoints
5:30 pm    Wrap-up and End of Workshop